A Plug-and-Play Volume Minimizing Micromixer

Abstract

Microscale fluid mixing has numerous applications where rapid and efficient mixing is required, including drug discovery, bio-analysis and point-of-care diagnostics. Conventional soft lithography processes, however, make the integration of robust and reliable mixing difficult to implement in practice, especially across different flow rates. Here a 3D-printed plug-in micromixer designed for rapid and modular integration with microfluidic devices that addresses long-standing integration challenges for micromixing in microfluidic devices is presented. The micromixer is based on the split-and-recombine (SAR) channel topology employing an optimized 3D geometry, minimizing internal volume and flui..